Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Obstructive sleep apnea and cardiac index.

C Guilleminault, J Motta, F Mihm

    Chest
    |March 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Search for Higgs Boson Pair Production in the Four b Quark Final State in Proton-Proton Collisions at sqrt[s]=13  TeV.

    Physical review letters·2022
    Same author

    Search for Flavor-Changing Neutral Current Interactions of the Top Quark and Higgs Boson in Final States with Two Photons in Proton-Proton Collisions at sqrt[s]=13  TeV.

    Physical review letters·2022
    Same author

    Observation of the B_{c}^{+} Meson in Pb-Pb and pp Collisions at sqrt[s_{NN}]=5.02  TeV and Measurement of its Nuclear Modification Factor.

    Physical review letters·2022
    Same author

    Observation of B <math></math> <math></math> <math></math> (2S)K <math> </math> and B <math></math> <math></math> <math></math> (2S)K <math></math> decays.

    The European physical journal. C, Particles and fields·2022
    Same author

    Measurement of the Inclusive and Differential Higgs Boson Production Cross Sections in the Decay Mode to a Pair of τ Leptons in pp Collisions at sqrt[s]=13  TeV.

    Physical review letters·2022
    Same author

    167&#x2003;Ovarian response and embryo production of cows superstimulated with different FSH regimens and inseminated with conventional or sex-sorted spermatozoa.

    Reproduction, fertility, and development·2022
    Same journal

    Redefining ILD Diagnosis Through the Bronchoscope: Molecular and Imaging Innovations.

    Chest·2026
    Same journal

    Longitudinal Mediastinal Lymph Node Dynamics Associate with Mortality and Fibrosis Progression in Fibrotic ILD.

    Chest·2026
    Same journal

    Prevalence, detection, and trajectory of combined pulmonary fibrosis and emphysema.

    Chest·2026
    Same journal

    Wearable-derived activity and physiological changes following pleural intervention in malignant pleural effusion.

    Chest·2026
    Same journal

    The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

    Chest·2026
    Same journal

    A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

    Chest·2026
    See all related articles

    Obstructive sleep apnea syndrome (OSAS) significantly reduces cardiac index during breathing pauses. Cardiac function recovers upon ventilation resumption, regardless of patient age or sleep stage.

    Area of Science:

    • Cardiology
    • Sleep Medicine
    • Physiology

    Background:

    • Obstructive sleep apnea syndrome (OSAS) is a common condition characterized by repeated upper airway collapse during sleep.
    • Hemodynamic alterations during OSAS are not fully understood, particularly concerning cardiac output.
    • Nocturnal polysomnography is the gold standard for diagnosing OSAS.

    Purpose of the Study:

    • To investigate the changes in cardiac index during apneic events in patients with severe OSAS.
    • To examine the impact of NREM and REM sleep on these hemodynamic alterations.
    • To determine if cardiac function recovers upon ventilation resumption.

    Main Methods:

    • Seventeen men with severe OSAS underwent polysomnography and hemodynamic monitoring during sleep.

    Related Experiment Videos

  • Cardiac index was measured using the thermodilution technique.
  • Apneic events and ventilation resumption were correlated with cardiac index changes.

    • Main Results:

    • A significant decrease in cardiac index was observed during apneic events compared to baseline.
    • Cardiac index significantly increased from baseline upon resumption of ventilation.
    • These changes were consistent across different patient ages and sleep stages (NREM and REM).

    Conclusions:

    • Severe OSAS leads to significant, transient reductions in cardiac index during apneic episodes.
    • Cardiac function demonstrates a rapid recovery following the restoration of ventilation.
    • Understanding these hemodynamic changes is crucial for managing patients with OSAS.