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Intrastromal Corneal Ring Segments and Keratoconus Progression: A Case Series Study
Blanca Benito-Pascual1, Pedro Arriola-Villalobos, Olivia Rodríguez-Quet
1Cornea Unit (B.B.-P.), Hospital Severo Ochoa, Madrid, Spain; Department of Ophthalmology (P.A.-V., R.C.-S., D.D.-V.), Department of Immunology, Ophthalmology and ENT, Faculty of Medicine, Universidad Complutense de Madrid (UCM) and IdISSC, Hospital Clínico San Carlos, Madrid, Spain; Department of Ophthalmology (O.R.-Q.), Hospital Clínico San Carlos and IdISSC, Madrid, Spain; and Department of Surgical and Clinical, Diagnostic and Pediatric Sciences (V.T.), Section of Ophthalmology, University of Pavia, IRCCS, Policlinico San Matteo, Pavia, Italy.
Objective:
To assess keratoconus (KC) progression following the implant of intrastromal corneal ring segments (ICRSs) in young patients.
Materials And Methods:
Retrospective, longitudinal, observational, controlled nonrandomized case series study. Keratoconus patients aged 25 years or younger who underwent uneventful ICRS surgery and completed at least 3 years of follow-up were enrolled. Controls were of similar age and treatment-naive patients with KC. The following Pentacam imaging (Oculus, Wetzlar, Germany) data were analyzed: keratometric (maximum, in-flattest meridian, in-steepest meridian, and mean), aberrometric (higher-order aberrations and coma), pachymetric (thinnest corneal thickness), and elevation (maximum posterior elevation). The main outcome measure was KC progression.
Results:
The study sample comprised 20 eyes of 18 cases (age 20.20 ± 3.70 years, nine right eyes, 14 male patients) and 30 eyes of 24 controls (age 20.80 ± 3.20 years, 15 right eyes, 21 male patients). The mean follow-up duration was 4.90 ± 1.70 years (range 3-8 years) for cases and 4.50 ± 1.40 years (range 3-8 years) for controls. Four cases and two controls met criteria for KC progression.
Conclusions:
Intrastromal corneal ring segments did not have significant impact on KC progression in the cohort.
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