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Author Spotlight: Multiplex Immunohistochemistry for Understanding Immune Regulation by Uterine NK Cells in Pregnancy
Published on: October 25, 2024
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Fertility outcomes post immune checkpoint inhibitor exposure
Emily C Harrold1, Martinique Ogle1, Erin O'Brien1
1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Cancer Cell
|November 1, 2024
Abstract
None:
Harrold et al. evaluate the fertility impact of checkpoint inhibitor blockade (ICB), demonstrating that unlike in utero exposure, post-exposure conception appears to result in uncomplicated pregnancies and healthy progeny. They demonstrate contemporaneous monitoring of temporal female hormonal fluctuations before, on, and post ICB exposure and prior to successful embryo implantation.
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