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Related Concept Videos

Dysrhythmias V: Evaluating Dysrhythmias01:30

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Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
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Related Experiment Video

Updated: May 1, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
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Improving the Assessment of Left Ventricular Diastolic Dysfunction by Including Left Atrial Strain in the Algorithm.

Lin Wang1, Jonathan Weber2, Jason Craft1

  • 1Division of Cardiac Imaging, St. Francis Hospital & Heart Center, Roslyn, New York; DeMatteis Cardiovascular Institute, St. Francis Hospital & Heart Center, Roslyn, New York.

Journal of Cardiac Failure
|November 1, 2024
PubMed
Summary
This summary is machine-generated.

Left atrial strain assessment resolves indeterminate left ventricular diastolic dysfunction (LVDD) cases. This method maintains accurate outcome risk stratification compared to current guidelines for LVDD diagnosis.

Keywords:
Diastolic dysfunctionDoppler echocardiographyleft atrial strainmyocardial fibrosis

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Diagnostic Algorithms

Background:

  • Current echocardiographic guidelines for left ventricular diastolic dysfunction (LVDD) frequently result in undetermined patient classifications.
  • A significant number of patients remain in an indeterminate category, necessitating improved diagnostic approaches.

Purpose of the Study:

  • To evaluate an alternative algorithm for assessing LVDD that incorporates left atrial (LA) strain as a tiebreaker.
  • To determine if this revised algorithm can resolve indeterminate LVDD classifications and its impact on outcome prediction.

Main Methods:

  • Retrospective analysis of 823 patients with concurrent echocardiography and cardiac magnetic resonance (CMR) within 7 days.
  • LVDD assessment using contemporary echocardiographic guidelines and a novel algorithm utilizing LA reservoir strain cutpoints (18%, 24%, 35%).
  • Correlation of LVDD status with LV myocardial scar burden via CMR and assessment of composite clinical outcomes.

Main Results:

  • Out of 823 patients, 275 (33%) had LVDD, with 117 (14%) classified as indeterminate.
  • Incorporating LA reservoir strain reclassified indeterminate cases into normal or LVDD categories.
  • The reclassification using LA strain provided outcome risk stratification comparable to existing guidelines.

Conclusions:

  • Left atrial reservoir strain effectively eliminates indeterminate LVDD classifications in echocardiographic assessments.
  • This enhanced diagnostic approach maintains the prognostic value of current LVDD guidelines.
  • LA strain serves as a valuable tool for refining LVDD diagnosis and patient risk stratification.