Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Arteries of the Lower Limbs01:24

Arteries of the Lower Limbs

178
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
178
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

892
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
892

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative systemic immune-inflammation index predicts seizure outcomes after anterior temporal lobectomy in drug-resistant temporal lobe epilepsy.

Seizure·2026
Same author

Biological age acceleration in primary aldosteronism: associations with renin, aldosterone, aldosterone-to-renin ratio, and left ventricular mass index.

Journal of hypertension·2026
Same author

Toward an AI Foundation Model Integrating Climate Change, Air Pollution, Socioeconomics, and Human Health.

Environmental science & technology·2026
Same author

Efficacy analysis of microvascular decompression and percutaneous balloon compression for trigeminal neuralgia secondary to vertebrobasilar dolichoectasia: a retrospective cohort study.

Acta neurochirurgica·2025
Same author

Clinical efficacy of unicompartmental knee arthroplasty on limb swelling, pain, and functional rehabilitation in knee osteoarthritis patients.

Journal of orthopaedic surgery and research·2025
Same author

Correlation of diabetes and adverse outcomes in hospitalized COVID-19 patients admitted to a tertiary hospital in China during a small-scale COVID-19 outbreak.

PeerJ·2025

Related Experiment Video

Updated: Jun 8, 2025

Simultaneous Video-EEG-ECG Monitoring to Identify Neurocardiac Dysfunction in Mouse Models of Epilepsy
11:54

Simultaneous Video-EEG-ECG Monitoring to Identify Neurocardiac Dysfunction in Mouse Models of Epilepsy

Published on: January 29, 2018

25.4K

Bidirectional association between abnormal cardiac conditions and epilepsy: A two-sample Mendelian randomization

Renfu Liu1, Yu Tian1, Xiangtao Zhang1

  • 1Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, Fujian, China; Department of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, Fujian, China.

Epilepsy & Behavior : E&B
|November 2, 2024
PubMed
Summary

This study reveals a two-way link between heart conditions like atrial fibrillation and valvular heart disease, and epilepsy. These cardiac issues increase epilepsy risk, while epilepsy can also lead to heart problems.

Keywords:
Cardiac ConditionsEpilepsyMendelian RandomizationNeuro-cardiac Interplay

More Related Videos

Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits
10:25

Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits

Published on: March 27, 2021

5.9K
Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

17.7K

Related Experiment Videos

Last Updated: Jun 8, 2025

Simultaneous Video-EEG-ECG Monitoring to Identify Neurocardiac Dysfunction in Mouse Models of Epilepsy
11:54

Simultaneous Video-EEG-ECG Monitoring to Identify Neurocardiac Dysfunction in Mouse Models of Epilepsy

Published on: January 29, 2018

25.4K
Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits
10:25

Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits

Published on: March 27, 2021

5.9K
Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

17.7K

Area of Science:

  • Cardiology
  • Neurology
  • Genetics

Background:

  • Observational studies suggest a link between cardiac conditions and epilepsy.
  • The precise nature and direction of this relationship are debated.
  • This study investigates the bidirectional association using Mendelian randomization.

Purpose of the Study:

  • To investigate the causal relationship between abnormal cardiac conditions and epilepsy.
  • To determine if cardiac conditions increase epilepsy risk and vice versa.
  • To explore the directionality of the association between epilepsy and heart diseases.

Main Methods:

  • Utilized a two-sample bidirectional Mendelian randomization (MR) approach.
  • Employed single nucleotide polymorphisms (SNPs) from large genome-wide association studies (FinnGen, UK Biobank).
  • Conducted sensitivity analyses using established MR methods (MR-Egger, weighted median, IVW, MR-PRESSO).

Main Results:

  • Forward MR suggested atrial fibrillation and flutter (AF) and valvular heart diseases (VHD) may increase epilepsy risk.
  • Reverse MR indicated epilepsy may increase susceptibility to AF, VHD, and heart failure.
  • A bidirectional relationship was observed between AF, VHD, and epilepsy.

Conclusions:

  • Findings support a bidirectional relationship between AF, VHD, and epilepsy.
  • Epilepsy may contribute to the development of heart failure.
  • Highlights the importance of cardiac screening in epilepsy patients and vice versa.