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Updated: Jun 13, 2025

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Temporal interaction of suicidal ideations and behaviors with loneliness in persistent depressive disorder - a
Johannes Wolf1,2, Stephan Goerigk3,4,5, Franziska Midderhoff3
1Department of Psychiatry and Psychotherapy, LMU University Hospital, Nussbaumstr. 7, 80336, Munich, Germany. johannes.wolf@med.uni-muenchen.de.
Abstract:
Individuals with persistent depressive disorder (PDD) are at increased risk for suicidality. Suicidality may be precipitated by loneliness. However, their temporal interplay in PDD has not been studied. We conducted a feasibility study using ecological momentary assessment (EMA) to measure short-term courses of suicidality and loneliness in 20 inpatients with PDD and current suicidality. EMA adherence of 13 completers was 81.3%. Suicidal ideations and loneliness varied with one standard deviation over three to six hours. This pilot study confirmed the feasibility of EMA in PDD and provided new insights in dynamics of suicidality and loneliness informing future study designs.
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