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Pseudotumour cerebri: incidence and pattern in North-Eastern Libya.

K Radhakrishnan, R Sridharan, P P Ashok

    European Neurology
    |January 1, 1986
    PubMed
    Summary

    This study documents 23 female patients with pseudotumor cerebri in Libya, finding a high incidence possibly linked to obesity. Visual impairment occurred in nearly half the patients, but without clear correlations to other factors.

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    Area of Science:

    • Neurology
    • Endocrinology
    • Ophthalmology

    Background:

    • Pseudotumor cerebri (idiopathic intracranial hypertension) is a neurological condition affecting cerebrospinal fluid pressure.
    • Understanding its prevalence and associated factors is crucial for early diagnosis and management.
    • Obesity and endocrine disorders are potential contributing factors.

    Purpose of the Study:

    • To document the incidence and clinical characteristics of pseudotumor cerebri in Benghazi, North-Eastern Libya.
    • To investigate potential associations with endocrine diseases and other risk factors.
    • To assess the prevalence and impact of visual impairment in affected patients.

    Main Methods:

    • Retrospective case documentation of 23 female patients over a 2-year period.

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  • Clinical, laboratory, and CT scan findings were analyzed.
  • Incidence rates were calculated for the local population.

    • Main Results:

    • 23 female patients diagnosed with pseudotumor cerebri; 21 idiopathic, 2 with endocrine diseases.
    • Significant obesity was noted in the patient group.
    • Moderate to severe visual loss occurred in 9 patients, with no clear correlation to duration, obesity, or other factors.
    • The observed incidence (1.7/100,000 total, 3.6/100,000 female) appears higher than reported elsewhere.
    • Idiopathic hypoparathyroidism identified in one case; hypothyroidism association suggested.

    Conclusions:

    • The incidence of pseudotumor cerebri in Benghazi may be higher than previously reported.
    • High obesity prevalence is a potential contributing factor to the increased occurrence.
    • Visual impairment is a significant complication, though its specific correlations remain unclear.