Related Experiment Video
Updated: Jun 8, 2025
10:42
Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids
Published on: August 10, 2016
18.0K
Advances and prospects for lactic acid production from lignocellulose
Ruofan Wu1, Jiahui Yang1, Yujia Jiang1
1State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, PR China.
Enzyme and Microbial Technology
|November 3, 2024
Summary
Microbial fermentation efficiently produces high-purity lactic acid from lignocellulose. This review covers microorganisms, sugar co-utilization, and consolidated bioprocessing for cost-effective lignocellulosic lactic acid production.
Area of Science:
- Biotechnology
- Industrial Microbiology
- Sustainable Chemistry
Background:
- Lactic acid is a key industrial chemical, with microbial fermentation yielding high optical purity.
- Lignocellulose is an abundant, renewable feedstock for bio-based chemical production.
- Current lignocellulosic lactic acid production faces cost and process complexity challenges.
Purpose of the Study:
- To comprehensively review current advancements in lactic acid production from lignocellulose.
- To discuss microorganisms, substrate utilization, and processing strategies.
- To explore consolidated bioprocessing for enhanced efficiency.
Main Methods:
- Review of literature on microbial lactic acid fermentation from lignocellulose.
- Analysis of co-utilization of glucose and xylose from lignocellulose hydrolysates.
- Discussion of consolidated bioprocessing strategies for integrated production.
Main Results:
- Microbial fermentation is the primary method for high-purity lactic acid production.
- Lignocellulose presents challenges due to its complex structure, impacting cost-effectiveness.
- Co-utilization of sugars and consolidated bioprocessing show promise for improved yields and reduced complexity.
Conclusions:
- Optimizing lactic acid production from lignocellulose is crucial for sustainable chemical manufacturing.
- Further research into consolidated bioprocessing can significantly improve process economics.
- Microbial platforms are central to unlocking the potential of lignocellulosic feedstocks.
Related Concept Videos
01:23Microbial Fermentation
1
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
1
01:20Fates of Pyruvate
8.4K
Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
8.4K
01:29Fermentation
113.4K
Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism.
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
113.4K
01:37The Citric Acid Cycle: Overview
16.2K
In aerobic organisms, the citric acid cycle is the second stage of cellular respiration wherein molecules derived from the breakdown of carbohydrates, proteins, and fats are oxidized into carbon dioxide and energy. This process is also known as the tricarboxylic acid (TCA) cycle as the first product of the cycle, citric acid, contains three carboxyl groups in its structure. Alternatively, this cycle is also referred to as the Krebs cycle, in honor of its discoverer Sir Hans Krebs.
The citric...
The citric...
16.2K