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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Sinonasal Specific Bone Lesions, Including Fibro-Osseous and Select Odontogenic Lesions
Jaylou M Velez Torres1, Darcy A Kerr2
1Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA. Electronic address: https://twitter.com/JaylouVelez.
Abstract:
Sinonasal bone lesions encompass a diverse spectrum, ranging from nonneoplastic and benign conditions to aggressive, malignant neoplasms. These lesions can affect individuals across various age groups, from pediatric to adult patients. Recognizing these entities is crucial, given the variability in treatment approaches, recurrence rates, and prognoses. This review explores the common and uncommon but distinctive bone lesions affecting the sinonasal region, highlighting key clinical, radiographic, morphologic, and genetic features for each. Additionally, we provide helpful tips on distinguishing and accurately classifying each lesion within its relevant differential diagnoses.
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