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Updated: Jun 8, 2025

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Hyponeophagia: A Measure of Anxiety in the Mouse
Published on: May 17, 2011
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Hypothalamic Hyperphagia in the Hospice Patient: Case Report and Discussion.
Paul Joseph1, Joseph Dixon1, Adam Marks1
1Division of Geriatric & Palliative Medicine (P.J., J.D., A.M.), University of Michigan, Ann Arbor, Michigan, USA.
Journal of Pain and Symptom Management
|November 4, 2024
Summary
Metformin effectively reduced insatiable appetite and overeating in a hospice patient with hypothalamic hyperphagia, a rare brain cancer complication. This suggests metformin as a potential palliative option for managing burdensome hyperphagia in end-of-life care.
Area of Science:
- Neuro-oncology
- Palliative Care
- Endocrinology
Background:
- Hypothalamic hyperphagia is a rare but debilitating complication of brain cancer.
- Managing excessive appetite and overeating in hospice patients presents significant challenges.
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