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Updated: Jun 8, 2025

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
A second chance for avatrombopag in chemotherapy-induced thrombocytopenia
Hanny Al-Samkari1,2, Donald C Moore3
1Division of Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Abstract:
Chemotherapy-induced thrombocytopenia (CIT) remains a common complication of cancer therapy with no approved available treatments in most of the world. Although a prior clinical trial of avatrombopag for CIT did not meet its primary end-point, a report from Galamaga and colleagues raises prospects for a second chance for avatrombopag in CIT, highlighting the differences between nadir and persistent CIT and the importance of patient selection in CIT treatment. Commentary on: Galamaga et al. Avatrombopag for the treatment of patients with chemotherapy-induced thrombocytopenia: a case series. Br J Haematol 2025; 206:272-278.
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