Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Phaco-Ersatz: cataract surgery designed to preserve accommodation.

J M Parel, H Gelender, W F Trefers

    Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
    |January 1, 1986
    PubMed
    Summary

    Phaco-Ersatz is a novel cataract surgery technique that recreates a physiologic lens in situ using a clear gel refill. This innovative approach shows surgical feasibility in experimental models for aphakia correction.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The anterior chamber of the eye as a clinical transplantation site for the treatment of diabetes: a study in a baboon model of diabetes.

    Diabetologia·2011
    Same author

    Optical profilometry of poly(methylmethacrylate) surfaces after reshaping with a scanning photorefractive keratectomy (SPRK) system.

    Applied optics·2010
    Same author

    Development of an algorithm for corneal reshaping with a scanning laser beam.

    Applied optics·2010
    Same author

    Transscleral Coulomb-controlled iontophoresis of methylprednisolone into the rabbit eye: influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels.

    Experimental eye research·2002
    Same author

    Slow release of acetylsalicylic acid by intravitreal silicone oil.

    Retina (Philadelphia, Pa.)·2001
    Same author

    Theoretical analysis of accommodation amplitude and ametropia correction by varying refractive index in Phaco-Ersatz.

    Optometry and vision science : official publication of the American Academy of Optometry·2001

    Area of Science:

    • Ophthalmology
    • Biomaterials Science
    • Surgical Innovation

    Background:

    • Cataract surgery involves removing the clouded natural lens.
    • Aphakia, the absence of the natural lens, requires correction.
    • Current intraocular lens implants aim to restore vision but have limitations.

    Purpose of the Study:

    • To introduce and evaluate the feasibility of the Phaco-Ersatz technique.
    • To explore a new method for correcting aphakia by recreating a functional lens.
    • To lay the groundwork for future research into the accommodative potential of the ersatz lens.

    Main Methods:

    • Phaco-Ersatz procedure: cataract removal while preserving the lens capsule.
    • Refilling the empty lens capsule with a biocompatible, optically clear gel.

    Related Experiment Videos

  • Surgical feasibility demonstrated in human cadaver eyes and in vivo animal models (rabbits, cats).

    • Main Results:

    • The Phaco-Ersatz surgical technique was demonstrated to be feasible.
    • The procedure successfully recreates a physiologic lens within the preserved natural lens capsule.
    • Experimental models confirmed the viability of the surgical approach.

    Conclusions:

    • Phaco-Ersatz offers a promising new surgical approach for cataract and aphakia correction.
    • The technique involves in situ reconstruction of a lens using a gel implant.
    • Further research is warranted to investigate the accommodative capabilities of this recreated lens.