Related Experiment Video
Updated: Jun 8, 2025
Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
Published on: June 21, 2019
Prevalence and risk factors for seizures in adult COVID-19 patients: A meta-analysis
Diogo Costa Garção1, Alisson Guilherme da Silva Correia2, Francisco José Silva Ferreira3
1Department of Morphology, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil; Neurosciences Study Group, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil; Department of Medicine, Tiradentes University, Aracaju, Sergipe, Brazil.
Abstract:
Seizures may be one of the neurological consequences of COVID-19. The present study aims to review the prevalence of seizures in COVID-19 patients considering sex and geographical origin. A review protocol was submitted to the PROSPERO database (CRD42021281467). PRISMA statement was used to report the meta-analysis. The authors selected studies for the meta-analysis by searching the principal databases. Studies were eligible if they reported seizures in COVID-19 patients, regardless of study design. Data were analyzed by proportion meta-analysis with a 95 % confidence interval (95 % CI). Cochran's Q and Higgins' I2 were used to measure heterogeneity. R software was used for meta-analysis. Subgroup analyses were carried out for sex, geographical origin of the subjects, and illness severity. A checklist for prevalence studies was used to assess the risk of bias in the included studies. A total of 32 studies (n = 251,997 analyzed patients) were included in this meta-analysis. A prevalence of 1.03 % (95 % CI 0.73 to 1.37, I2 = 93 %, p < 0.001) was found. No statistically significant differences were found in the analysis by geographical subgroups. Men were found to be less likely to had COVID-19 seizures (OR = 0.75, 95 % CI 0.21-2.74), while mildly ill patients were found to be more likely to had COVID-19-induced seizures (OR = 2.08, 95 % CI 0.86-5.06). Our results show a slight prevalence of seizures in COVID-19 patients. In addition, we found that the groups analyzed had differences in the odds of having COVID-19-induced seizures.
More Related Videos
Related Concept Videos
01:13Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
01:24Arteries of the Lower Limbs
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
01:18Antiepileptic Drugs: GABAergic Pathway Potentiators
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
01:20COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
01:20Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...