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Updated: Jun 8, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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Exploring the reactivity of bicyclic α-iminophosphonates to access new imidazoline I2 receptor ligands

Andrea Bagán1, Sònia Abás1, Judith Palà-Pujadas1

  • 1Laboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, E-08028 Barcelona, Spain.

Bioorganic Chemistry
|November 4, 2024
PubMed

Keywords:
Alzheimer’s diseaseBicyclic α-aminophosphonateBicyclic α-phosphoprolineCaenorhabditis elegansImidazoline I(2) receptorsNeuroinflammationNeuroprotectionParkinsonismimidazoline I(2) receptor ligands

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