[Advances on Molecular Mechanism and Clinical Treatment 
in Invasive Mucinous Adenocarcinoma]

Minjun Shi1, Bo Ye1

  • 1Department of Thoratic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 
Shanghai 200030, China.

Invasive mucinous adenocarcinoma (IMA) is a special type of lung adenocarcinoma that accounts for 2% to 10% of all lung adenocarcinoma. Surgical treatment is preferred for IMA, and traditional chemotherapy drugs and targeted therapy drugs have poor efficacy in this disease. IMA has unique prognostic, imaging and molecular features. The incidence of IMA is very low, so thoracic surgeons may lack of knowledge to the disease and misdiagnose it as benign diseases such as pneumonia and tuberculosis. This article reviews and discusses the imaging, clinicopathological features, treatment methods and prognosis of IMA.
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