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Hypoactive Delirium: A Rare Manifestation of Scrub Typhus

Asif Dabeer Jafri1, Srikant K Dhar2, Chitralekha Naik3

  • 1General Medicine, SUM Ultimate Medicare, Bhubaneswar, IND.

Cureus
|November 4, 2024
PubMed

Insights

Scrub typhus can cause severe illness, including rare neuropsychiatric symptoms like hypoactive delirium. Early recognition is crucial, as these symptoms can be subtle and easily missed, leading to underdiagnosis.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Critical Care Medicine

Background:

  • Scrub typhus, a bacterial infection transmitted by mites, presents a wide range of clinical manifestations, from mild fever to severe organ dysfunction.
  • Neuropsychiatric complications are uncommon but recognized sequelae of scrub typhus.

Observation:

  • A 60-year-old male presented with fever and headache, later developing hypoactive delirium during hospitalization.
  • Metabolic, autoimmune, and other infectious causes for the delirium were systematically excluded.

Findings:

  • The patient was diagnosed with hypoactive delirium secondary to scrub typhus.
  • This case underscores the often nonspecific and easily overlooked presentation of delirium in scrub typhus.

Implications:

  • Highlights the importance of considering scrub typhus in endemic areas, even with atypical neuropsychiatric symptoms.
  • Emphasizes the diagnostic challenge posed by hypoactive delirium, potentially leading to underdiagnosis and delayed treatment.
Keywords:
hypoactive deliriummodafinil in scrub typhusneuroimaging in scrub tyhusneuropsychiatric symptoms in scrub typhusscrub typhus treatment

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