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Updated: Jun 8, 2025

Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models
Published on: March 24, 2019
Editorial: Protein post-translational modifications in the nervous system: from development to disease and ageing
Beatriz Alvarez1,2, Judit Symmank3, Geraldine Zimmer-Bensch4
1Department of Biochemistry and Molecular Biology, Veterinary School, Complutense University of Madrid, Madrid, Spain.
Abstract:
PTMs are crucial for biological processes contributing to healthy organ function. Protein post-translational modifications (PTMs), such as phosphorylation (P), acetylation (Ac), SUMOylation (SUMO), S-nitrosylation (Nitro), ubiquitination (Ub) and glycosylation (Glyco), affect a wide range of cellular and biological functions as depicted in this cartoon. Perturbations lead to severe consequences for the normal function of the brain and other organs, such as muscle. Created in BioRender. Hübner (2024) BioRender.com/j49w898.
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