Alcohol-Induced & Drug-Induced Deaths in Hawai'i During the COVID-19 Pandemic

Nash A K Witten1, Clark Caballero2

  • 1Department of Family Medicine and Community Health, John A. Burns School of Medicine, University of Hawai'i, Aiea, HI (NAKW).

Insights

The COVID-19 pandemic saw rising alcohol and drug-induced deaths nationwide. However, Hawai

Area of Science:

  • Public Health
  • Epidemiology
  • Toxicology

Background:

  • The COVID-19 pandemic correlated with increased alcohol- and drug-induced mortality in the United States.
  • Pre-pandemic trends in mortality require examination in the context of pandemic-related societal changes.

Purpose of the Study:

  • To analyze alcohol- and drug-induced mortality trends in Hawai'i during the COVID-19 pandemic.
  • To compare Hawai'i's mortality data with national trends from 2018 to 2021.

Main Methods:

  • Utilized the Centers for Disease Control and Prevention's Underlying Cause of Death database.
  • Compared age-adjusted rates of alcohol-induced, drug-induced, and all-cause deaths for individuals aged 15+.
  • Analyzed data from 2018 through 2021, encompassing pre-pandemic and pandemic years.

Main Results:

  • Both the US and Hawai'i experienced annual increases in alcohol- and drug-induced deaths from 2018 to 2021.
  • Alcohol-related deaths in Hawai'i mirrored the increasing national trend during the pandemic.
  • Conversely, Hawai'i observed a decrease in the age-adjusted rate of drug-induced deaths between 2020 and 2021.

Conclusions:

  • Alcohol-induced mortality in Hawai'i rose in parallel with the US during the COVID-19 pandemic.
  • Hawai'i demonstrated a unique trend with a decline in drug-induced deaths, contrasting with national increases.
  • Pandemic-related mortality patterns for substance-induced deaths vary geographically, necessitating localized public health strategies.

Related Concept Videos

Depressants01:28

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
99
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
175
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
26
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
160
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
445
Hepatic Drug Excretion: Influencing Factors01:16

Hepatic Drug Excretion: Influencing Factors

The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
94