Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

5.8K
Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
5.8K
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

2.7K
In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent Progress in the Development of Selective MAGL Modulators (2020-2026).

Molecules (Basel, Switzerland)·2026
Same author

Ivermectin effects in cultured endothelial cells from porcine corpus luteum.

Environmental toxicology and pharmacology·2026
Same author

Diagnosis and Treatment of Cystitis in Dogs: An Italian Survey.

Veterinary sciences·2026
Same author

Influence of management and air quality conditions on development of respiratory and gastroenteric disease, and antibiotics phenotypic resistance in domestic canaries (<i>Serinus canaria domesticus</i>).

Avian pathology : journal of the W.V.P.A·2026
Same author

Risk prioritisation of (emerging) contaminants in aquaculture production.

EFSA journal. European Food Safety Authority·2025
Same author

Fipronil presence in feed materials: hints for a geographical risk analysis to support the transition towards safe and sustainable food systems.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment·2025

Related Experiment Video

Updated: May 7, 2026

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS
07:34

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS

Published on: March 14, 2013

12.7K

Advanced LC-MS/MS Technique for Environmental Ivermectin Detection.

Alicia Maria Carrillo Heredero1, Giulia Segato2, Simonetta Menotta2

  • 1Department of Veterinary Sciences, University of Parma, Strada del Taglio 10, Parma 43126, Italy.

ACS Omega
|November 4, 2024
PubMed
Summary

A new, validated method accurately detects ivermectin in environmental samples like feces, soil, and sewage. This sensitive assay is crucial for monitoring ivermectin

More Related Videos

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques
09:36

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Published on: March 8, 2024

741
Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry
08:56

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Published on: November 22, 2024

566

Related Experiment Videos

Last Updated: May 7, 2026

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS
07:34

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS

Published on: March 14, 2013

12.7K
Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques
09:36

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Published on: March 8, 2024

741
Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry
08:56

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Published on: November 22, 2024

566

Area of Science:

  • Environmental Chemistry
  • Analytical Chemistry
  • Ecotoxicology

Background:

  • Ivermectin, a broad-spectrum antiparasitic, poses toxicity risks to non-target aquatic and insect species.
  • Existing detection methods lack the required accuracy and sensitivity for comprehensive environmental monitoring.
  • Understanding ivermectin's environmental fate necessitates precise quantification in diverse matrices.

Purpose of the Study:

  • To develop and validate a highly accurate analytical method for ivermectin detection.
  • To assess ivermectin levels in environmental samples including feces, soil, and sewage.
  • To establish a sensitive assay for environmental risk assessment and monitoring.

Main Methods:

  • Method development and validation following Eurachem guidelines.
  • Quantification of ivermectin in feces, soil, and sewage matrices.
  • Determination of method's limit of detection (LOD) and limit of quantification (LOQ).

Main Results:

  • The validated method demonstrated high linearity (R² ≥ 0.99) and recovery rates (92-96%).
  • Low limits of detection were achieved: 0.66 μg/kg (feces), 0.54 μg/kg (soil), and 0.36 μg/kg (sewage).
  • The method was successfully applied to analyze 333 environmental samples.

Conclusions:

  • A precise and sensitive method for ivermectin detection in environmental matrices was successfully developed and validated.
  • This assay enables accurate ivermectin quantification, supporting environmental monitoring and risk assessment.
  • The method's robustness and sensitivity offer improved capabilities for ecotoxicological studies.