What intrinsic factors affect the central corneal thickness?

Area of Science:

• Ophthalmology
• Corneal Science
• Ocular Biomechanics

Background:

• The cornea protects the eye's inner structures.
• Central corneal thickness (CCT) is a key ocular measurement.
• CCT influences intraocular pressure (IOP) assessment and surgical decisions.

Purpose of the Study:

• To comprehensively review factors influencing central corneal thickness (CCT).
• To enhance understanding of corneal dynamics.
• To contribute to improved diagnostic and therapeutic strategies in ophthalmology.

Main Methods:

• Literature review of studies on central corneal thickness.
• Analysis of factors affecting corneal thickness.
• Synthesis of current knowledge on CCT determinants.

Main Results:

• Identified multiple factors influencing CCT.
• Highlighted the clinical significance of CCT in various ophthalmic applications.
• Emphasized the role of CCT in refractive surgery and disease management.

Conclusions:

• Understanding factors affecting CCT is vital for accurate ophthalmic assessments.
• Knowledge of CCT variability aids in personalized patient care.
• This review provides a foundation for refining ophthalmic diagnostic and surgical approaches.