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Liquid chromatographic method for perphenazine and its sulfoxide in pharmaceutical dosage forms for determination of
Journal - Association of Official Analytical Chemists
|January 1, 1986
Abstract:
A liquid chromatographic method is described for determination of perphenazine and perphenazine sulfoxide in representative dosage forms. Sulfoxide levels were nondetectable or less than 1% in tablets and in an injectable product. Sulfoxide levels increase with time in some syrup formulations and may be as high as 11% in syrup formulations before their expiration date.