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Related Concept Videos

Mitral Regurgitation II: Clinical features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical features and Diagnostic Tests

5
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
5
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

3
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
3
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

7
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
7
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

147
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
147
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  11. Accuracy Of Mitral Annular Plane Systolic Excursion In Diagnosing Anthracycline-induced Subclinical Cardiotoxicity In Patients With Breast Cancer - A Retrospective Cohort Study

Accuracy of mitral annular plane systolic excursion in diagnosing anthracycline-induced subclinical cardiotoxicity in patients with breast cancer - a retrospective cohort study

Luís Fábio Barbosa Botelho1, Marcelo Dantas Tavares de Melo2, André Luiz Cerqueira de Almeida3

  • 1Department of Internal Medicine, Federal University of Paraiba, Rua da Aurora 333, Ap 904, João Pessoa, 58043-900, João Pessoa, PB, Brazil. fabinhobot@hotmail.com.

Cardio-Oncology (London, England)
|November 4, 2024

Related Experiment Videos

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
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Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

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Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk Evaluation
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Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk Evaluation

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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Published on: February 12, 2011

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View abstract on PubMed

Summary
This summary is machine-generated.

Mitral annular plane systolic excursion (MAPSE) accurately detects early heart damage in breast cancer patients receiving anthracycline chemotherapy. This method is as effective as global longitudinal strain (GLS) for diagnosing subclinical cardiotoxicity.

Area of Science:

  • Cardiology
  • Oncology
  • Medical Imaging

Background:

  • The mitral annular plane systolic excursion (MAPSE) assesses left ventricle longitudinal function.
  • Its diagnostic accuracy for cardiotoxicity in oncological patients remains unclear.
  • This study evaluates MAPSE for detecting subclinical cardiotoxicity in breast cancer patients undergoing anthracycline treatment.

Purpose of the Study:

  • To assess the accuracy of MAPSE in diagnosing subclinical cardiotoxicity.
  • To compare MAPSE with global longitudinal strain (GLS) in this patient population.

Main Methods:

  • Retrospective cohort study of breast cancer patients treated with anthracyclines.
  • Echocardiographic assessments including left ventricular ejection fraction (LVEF) and MAPSE were performed at multiple time points.
Keywords:
AnthracyclinesCancerCardiotoxicityEchocardiography

Related Experiment Videos

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
12:24

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

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Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk Evaluation
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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
07:21

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Published on: February 12, 2011

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  • Receiver operating characteristic (ROC) curve analysis was used to evaluate the diagnostic performance of MAPSE and GLS.

    • Main Results:

    • Sixty-one patients were included; 8.2% developed cardiotoxicity.
    • Cardiotoxic patients showed significantly lower LVEF, MAPSE, and GLS.
    • A 15% relative reduction in MAPSE demonstrated 80% sensitivity and 77% specificity for cardiotoxicity detection.

    Conclusions:

    • MAPSE is a valuable tool for diagnosing subclinical cardiotoxicity in breast cancer patients.
    • MAPSE exhibits comparable accuracy to GLS in this clinical setting.
    Global longitudinal strain
    MAPSE