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Leveraging foundation and large language models in medical artificial intelligence
Io Nam Wong1, Olivia Monteiro1, Daniel T Baptista-Hon1
1Institute for AI in Medicine, Faculty of Medicine, Macau University of Science and Technology, Macau Special Administrative Region 999078, China.
Chinese Medical Journal
|November 5, 2024
Summary
Foundational and large language models (LLMs) are transforming medical artificial intelligence (AI). This review classifies AI models and discusses challenges in data, evaluation, and regulation for responsible healthcare integration.
Area of Science:
- Medical Artificial Intelligence
- Machine Learning in Healthcare
- Clinical Applications of AI
Background:
- Foundational and large language models (LLMs) are increasingly prevalent in medical AI.
- These advanced AI models offer significant potential for healthcare applications.
Purpose of the Study:
- To review the applications of foundational and LLMs in medical AI.
- To introduce a novel classification framework for medical AI models.
- To address challenges and considerations for implementing AI in healthcare.
Main Methods:
- Literature review of recent advancements in medical AI.
- Development of a classification system for AI models (disease-specific, general-domain, multi-modal).
- Analysis of challenges including data acquisition, augmentation, fusion, and privacy.
Main Results:
- A new framework categorizes medical AI models into three types.
- Key challenges in data handling, model evaluation, and regulatory oversight are identified.
- The transformative potential of AI in healthcare is highlighted.
Conclusions:
- Responsible integration of AI in healthcare requires addressing data, evaluation, and regulatory challenges.
- Continuous improvement, data security, and standardized evaluations are crucial.
- Collaborative approaches are essential for the effective use of AI in clinical settings.

