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Related Experiment Video

Updated: Jun 8, 2025

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
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Anthrax: A narrative review.

Sumel Ashique1,2, Aritra Biswas3,4, Sourav Mohanto5

  • 1School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India.

New Microbes and New Infections
|November 5, 2024
PubMed
Summary

Bacillus anthracis causes anthrax, a global zoonotic threat. This review examines current human anthrax epidemiology, diagnosis, and treatment, highlighting the need for updated prevention and therapeutic strategies against this infectious disease.

Keywords:
AnthraxAnti-microbial resistanceDiagnosisInfectious diseasePandemicTravel disease

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Area of Science:

  • Microbiology
  • Epidemiology
  • Infectious Diseases

Background:

  • Bacillus anthracis is a zoonotic bacterium causing anthrax in humans and animals.
  • Herbivorous animals are reservoirs, with all endothermic species susceptible.
  • Human infection occurs through contact with infected animals/products or contaminated flesh.

Purpose of the Study:

  • To review the current epidemiological situation of human anthrax globally.
  • To examine altered symptoms, transmission routes, and diagnostic methods.
  • To assess available therapies, vaccines, and future treatment perspectives.

Main Methods:

  • Narrative review based on literature search of PubMed, ScienceDirect, and ClinicalTrials.gov.
  • Keywords included "Anthrax" combined with "Infection", "Pandemic", "Infectious disease", "Vaccine", and "Diagnosis".
  • Focused on literature published between 2005 and 2024.

Main Results:

  • Minimal recent narrative literature on human anthrax was identified.
  • The review highlights various potential human infections, including pneumonia and CNS infections.
  • Current diagnostic and therapeutic strategies are examined.

Conclusions:

  • Urgent examination of human anthrax epidemiology in densely populated areas is crucial.
  • Development of enhanced diagnostic approaches and prevention protocols is needed.
  • Future research should focus on novel therapeutics and vaccine development for anthrax prevention.