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Related Experiment Video

Updated: Jun 8, 2025

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
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The 'DIMPLE SIGN' of Intra-Aortic Cord.

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  • 1Leeds Vascular Unit and University of Leeds, Leeds Teaching Hospital NHS Trust, Leeds, UK.

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A unique imaging sign, the 'Dimple sign', helps differentiate intra-aortic cords from dissection intimal flaps. This finding aids in avoiding unnecessary surgery or prolonged surveillance for aortic abnormalities.

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CT angiogram and dimplecordintra-aortic

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Area of Science:

  • Medical imaging
  • Cardiovascular radiology
  • Diagnostic techniques

Background:

  • Increasingly sophisticated imaging reveals rarer aortic anomalies.
  • Intra-aortic cords require differentiation from intimal flaps to guide treatment.
  • Accurate diagnosis prevents unnecessary surgical intervention or extended patient monitoring.

Purpose of the Study:

  • To identify and establish the diagnostic utility of the 'Dimple sign' for intra-aortic cords.
  • To differentiate intra-aortic cords from intimal flaps using advanced imaging.
  • To analyze imaging findings in institutional and published cases.

Main Methods:

  • Retrospective review of institutional imaging cases (2) and published literature (6).
  • Focus on identifying a unique sign on volume rendering reformatting of the aorta.
  • Correlation of imaging findings with clinical diagnoses.

Main Results:

  • The 'Dimple sign' was observed in 6 out of 8 total cases (institutional and published).
  • This sign, unique to intra-aortic cords, arises from the cord tethering to the aortic wall.
  • The dimple represents an inward umbilication of the aortic wall, visible on volume rendering.

Conclusions:

  • The 'Dimple sign' is a reliable indicator for diagnosing intra-aortic cords.
  • Volume and cinematic rendering facilitate easy identification of the 'Dimple sign'.
  • This sign is crucial for differentiating intra-aortic cords from intimal flaps, optimizing patient management.