Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Abnormal Proliferation

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

Abnormal Proliferation

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

Papillary Dermis

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

Accessory Structures of the Skin: Nails

Accessory Structures of the Skin: Nails

Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Diabetic Foot Ulcer

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2026

Same author

A life without a past.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2026

Same author

Is it possible to sneeze your way out of epilepsy?

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2025

Same author

A hundred years of EEG.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2025

Same author

The first victim of international cross-country skiing.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2024

Same author

Post-stroke epilepsy.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2024

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

[Glomus tumour under the nail].

Karl O Nakken¹, Lillian Nordbø Berge², Geir D Slapø³

¹Spesialsykehuset for epilepsi, Oslo universitetssykehus.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke

|November 5, 2024

Summary

This summary is machine-generated.

Glomus tumours are rare, benign growths causing significant thumb pain. Delayed diagnosis of this treatable condition can lead to chronic disability.

More Related Videos

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Published on: February 28, 2025

Related Experiment Videos

Last Updated: Jun 23, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Published on: February 28, 2025

Area of Science:

Oncology
Dermatology
Hand Surgery

Context:

Presents a case of a young female with persistent left thumb pain unresponsive to conservative treatment.
Initial misdiagnoses included common conditions like carpal tunnel syndrome and tennis elbow.
Symptoms were exacerbated by cold and pressure, characteristic of glomus tumour but initially overlooked.

Purpose:

To highlight the diagnostic challenges associated with glomus tumours.
To emphasize the importance of considering rare diagnoses in cases of unexplained chronic pain.
To illustrate the potential for delayed diagnosis to result in significant patient morbidity.

Summary:

A rare benign hypervascular lesion, glomus tumour, typically affects the subungual region.
The patient presented with symptoms mimicking other conditions, leading to a diagnostic delay.
Successful treatment is possible, but delayed diagnosis can cause long-term disability.

Impact:

Underscores the need for increased physician awareness of glomus tumours.
Demonstrates how a rare condition can cause prolonged suffering and disability if not promptly identified.
Emphasizes the importance of a thorough diagnostic workup for persistent, unexplained pain, especially in the extremities.