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Related Experiment Video

Updated: May 1, 2026

Determination of the Excitation and Coupling Rates Between Light Emitters and Surface Plasmon Polaritons

Determination of the Excitation and Coupling Rates Between Light Emitters and Surface Plasmon Polaritons

Published on: July 21, 2018

Helicoid Grating-Coupled Surface Plasmon Resonance Sensor.

Ryeong Myeong Kim¹, Soo Min Lee¹, Jeong Hyun Han¹

¹Department of Materials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea.

|November 5, 2024

Summary

This summary is machine-generated.

This study introduces a novel plasmonic metamaterial biosensor for ultrasensitive detection. The circular dichroism (CD) response enhances reliability and sensitivity for biomedical diagnostics.

Keywords:

2D helicoid crystal Grating-coupled SPR and plasmonic biosensing chiral gold nanoparticles circular dichroism helicoids

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Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

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Published on: March 17, 2023

Area of Science:

Nanotechnology
Biomedical Diagnostics
Optical Sensing

Background:

Ultrasensitive biomolecular sensing is crucial for real-time biomedical diagnostics.
Plasmonic biosensing offers noninvasive, high-sensitivity detection via light-molecule interactions.
Existing methods require improvements in sensitivity and reliability for trace sample detection.

Purpose of the Study:

To develop a novel plasmonic metamaterial-based sensing strategy for enhanced biomolecular detection.
To utilize the circular dichroism (CD) response from chiral nanoparticle gratings for improved sensing performance.
To achieve high sensitivity and reliability in optical biosensing applications.

Main Methods:

Fabrication of a chiral nanoparticle grating structure (2D helicoid crystal) on a gold substrate.
Utilizing grating-coupled surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR) coupling.
Measuring the circular dichroism (CD) response, specifically the CD/g_reflection, in the SPR mode.

Main Results:

Achieved a strong chiroptic response by spectrally coupling SPR and LSPR in helicoids.
Demonstrated a remarkable CD/g_reflection response in the SPR mode.
Attained a sensitivity of 379.2 nm/RIU and a detection limit of a few mM for d-glucose.

Conclusions:

The SPR-CD-based approach offers a new paradigm for high-performance optical biosensors.
The differential CD response effectively corrects optical fluctuations, enhancing sensitivity and reliability.
This method provides a promising platform for ultrasensitive, rapid, and reliable biomolecular sensing.