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Two Cases of FAVA With an Uncommon Localization in Adults
Angel Fernandez-Flores1,2,3, José Luis Martínez-Amo4
1Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.
Fibroadipose vascular anomalies (FAVA) are rare vascular malformations often misdiagnosed as lipomas. This study highlights two atypical FAVA cases, emphasizing their distinct histopathological features for accurate diagnosis.
Area of Science:
- Dermatopathology
- Vascular Malformations
- Histopathology
Background:
- Fibroadipose vascular anomaly (FAVA) is a rare vascular malformation.
- Often misdiagnosed as lipomas due to intramuscular location.
- First described in 2014, potentially leading to underdiagnosis in archives.
Observation:
- Presents two cases of FAVA with atypical clinical features.
- Atypical features include unusual topography and age of onset.
- Histopathological examination reveals characteristic fibroadipose tissue and dysmorphic venous vessels.
Findings:
- Histopathology confirms typical FAVA features despite atypical clinical presentation.
- Dysmorphic venous vessels dissecting striated muscle are key findings.
- FAVA requires differentiation from other intramuscular vascular anomalies.
Implications:
- Highlights the importance of histopathological analysis for FAVA diagnosis.
- Suggests re-evaluation of archived cases with similar features.
- Aids dermatologists in recognizing and correctly diagnosing FAVA, improving patient management.
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