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Using shock index, pediatric age adjusted (SIPA) to predict prolonged length of stay in perforated appendicitis: a
Alexandra Barone-Camp1, Amanda Louiselle2, Samantha Bothwell3
1Division of Pediatric Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 E 16th Ave. Box 323, Aurora, CO, 80045, USA. alexandra.barone-camp@cuanschutz.edu.
Insights
Elevated Shock Index, Pediatric Age Adjusted (SIPA) in children with appendicitis indicates a higher risk of perforation and predicts longer hospital stays. This finding supports using SIPA for triage and family counseling.
Area of Science:
- Pediatric Surgery
- Emergency Medicine
- Clinical Outcomes Research
Background:
- Hospital length of stay (LOS) for pediatric appendicitis is challenging to predict.
- Shock Index, Pediatric Age Adjusted (SIPA) is a validated tool for identifying severe injury and predicting mortality in pediatric trauma and ICU patients.
Purpose of the Study:
- To determine if elevated SIPA at presentation and its normalization time can identify children with perforated appendicitis.
- To assess if SIPA can predict hospital LOS in pediatric appendicitis cases.
Main Methods:
- Retrospective cohort study of 169 children (1-17 years) admitted for appendicitis in 2021.
- Primary outcomes: perforated appendicitis and hospital LOS.
- Generalized linear regressions adjusted for age, sex, fecalith, temperature, and time to OR.
Main Results:
- Elevated SIPA was significantly associated with perforated appendicitis (p=0.0002) and longer hospital LOS (p<0.0001).
- Patients with elevated SIPA had 5.4 times higher odds of perforation and 2.0 times longer LOS.
- Elevated SIPA also predicted longer recovery times, including toleration of regular diet and duration of antibiotics.
Conclusions:
- Elevated SIPA at presentation is a strong indicator of perforated appendicitis in children.
- Incorporating SIPA into the triage process for appendicitis can improve patient identification and management.
- SIPA can aid in counseling families regarding expected recovery trajectories.
Purpose:
Hospital length of stay (LOS) following admission for appendicitis is difficult to predict. Shock index, pediatric age adjusted (SIPA) accurately identifies severely injured trauma patients and predicts mortality among children admitted to the ICU. Our aim was to determine if elevated SIPA at presentation, and time to normalization of SIPA, can identify children with perforated appendicitis and predict hospital LOS.
Methods:
This was a retrospective cohort study of children 1-17 years admitted to a quaternary care referral center with appendicitis after appendectomy in 2021. The primary outcomes were presence of perforated appendicitis and hospital LOS. Generalized linear regressions were performed. Covariates included in all models were age, sex, fecalith, initial temperature, and time from diagnosis to OR.
Results:
We included 169 patients; 53 (31.4%) had perforated appendicitis. After adjustment, elevated SIPA was associated with presence of perforated appendicitis (p = 0.0002) and longer LOS (p < 0.0001). A patient presenting with appendicitis and elevated SIPA had 5.447 times higher odds of having perforated appendicitis (95% CI: 2.262, 13.826), a mean hospital LOS 2.047 times longer (95% CI: 1.564, 2.683), a mean time to toleration of regular diet 4.995 times longer (95% CI: 2.914, 8.918), and a mean duration of antibiotics that is 1.761 times longer (95% CI: 1.383, 2.243) than a patient with normal SIPA.
Conclusion:
In children with appendicitis, elevated SIPA at presentation is associated with higher risk of perforation. These findings support the incorporation of SIPA during triage of patients with appendicitis and counseling families after surgery.
Level Of Evidence:
Level 3.
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