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Updated: Jun 8, 2025

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An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
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Paracetamol versus ibuprofen for early postpartum pain control: a randomized controlled trial
Shai Ram1, Dotan Madar2, Hila Shalev Ram3,4
1Lis Maternity and Women's Hospital, 6 Weitzman St, 6423906, Tel Aviv, Israel. shairam85@gmail.com.
Archives of Gynecology and Obstetrics
|November 5, 2024
Summary
Paracetamol and ibuprofen are equally effective for postpartum pain relief after vaginal birth. Both non-opioid options provide similar pain control and do not affect breastfeeding or mobilization.
Area of Science:
- Obstetrics and Gynecology
- Pain Management
- Pharmacology
Background:
- Postpartum pain is common after vaginal delivery.
- Effective non-opioid analgesics are needed for pain management.
- Paracetamol and ibuprofen are commonly used analgesics.
Purpose of the Study:
- To compare the effectiveness of paracetamol and ibuprofen for postpartum pain control.
- To evaluate non-opioid pain management strategies after vaginal delivery.
Main Methods:
- Randomized controlled trial involving 107 women post-vaginal birth.
- Participants received either 1000 mg paracetamol or 400 mg ibuprofen.
- Pain assessed using a numeric rating scale (NRS) at multiple time points.
Main Results:
- No significant differences in pain levels (NRS) between paracetamol and ibuprofen groups.
- Similar outcomes in time to breastfeeding initiation, mobilization, and urination.
- No difference in the need for additional analgesia between the two groups.
Conclusions:
- Paracetamol and ibuprofen are equivalent non-opioid alternatives for postpartum pain.
- Both medications offer effective pain management without adverse effects on key postpartum recovery indicators.

