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Surrogate End Points in Apolipoprotein L1 - Associated Kidney Disease : Evaluation in Three Cohorts

Alix T Rosenberg1, Carina Flaherty1, Amanda H Anderson2

  • 1Division of Precision Medicine, Department of Medicine, New York University, New York, New York.

Clinical Journal of the American Society of Nephrology : CJASN
|November 5, 2024
PubMed
Abstract

No abstract available in PubMed .

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Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
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