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Updated: Jun 8, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Multidimensional Assessment of Physical Function for People in Dialysis: The Rehabilitation in Hemodialysis Area
Alessandro Capitanini1, Fiammetta Ravaglia2, Matteo Paci3
1San Jacopo Hospital, Azienda USL Toscana Centro, Pistoia, Italy.
Background:
Physical performance is poorly addressed in dialysis patients, due to several clinical and organizational barriers. In this study we investigated the physical functional status of a cohort of dialysis patients, using a multidimensional assessment.
Methods:
Four hundred and forty-six individuals from 8 hemodialysis centers (176 females), mean age 67.5 ± 14.1 years, and dialysis vintage 62 ± 72.1 months, were assessed by a multidimensional battery including Short Form Health Survey (SF12), Elderly Falls Screening Test (EFST), Short Physical Performance Battery (SPPB), and Handgrip Strength Test (HST). Individuals were stratified into 3 groups (poor, moderate, and good performers) according to the SPPB score. Functional assessments were performed by staff nurses, with the support of physiotherapists and nephrologists.
Results:
According to SPPB, 53.4% of dialysis patients showed a severe physical impairment. A significant difference emerged among the 3 SPPB groups for age, HST, EFST, and SF12. The main predictors of the SPPB score group were age (p = 0.0001), EFST (p = 0.028 moderate performers and p = 0.0001 poor performers), dominant HST (p = 0.04 moderate performers), and SF12 physical (p = 0.003 moderate performers and p = 0.0001 poor performers). Each age group showed physical performance comparable to a healthy general population of 10 years older.
Conclusions:
Our results confirmed the severe impairment of physical function in the end stage kidney disease population. The multidimensional assessment showed that SPPB test is an effective tool to stratify the dialysis population. Moreover, EFST, HST, and SF12 may contribute to the definition of a tailored physical activity program based on patient characteristics.
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