Related Experiment Video

Updated: Jun 8, 2025

Purification and Reconstitution of TRPV1 for Spectroscopic Analysis
11:53

Purification and Reconstitution of TRPV1 for Spectroscopic Analysis

Published on: July 3, 2018

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Structure-function analyses of human TRPV6 ancestral and derived haplotypes.

Arthur Neuberger1, Alexey Shalygin2, Yury A Trofimov3

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

Structure (London, England : 1993)
|November 5, 2024
PubMed
Summary

TRPV6 calcium channels, differing by genetic variations, show similar structures and functions. These findings suggest other factors influence cancer susceptibility in patients of African ancestry.

Keywords:
TRP channelsTRPV6ancestralcancercryo-EMderiveddynamic molecular portraits of TRPV6 pore domainoncochannel

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