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Updated: Jun 8, 2025

Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice
Published on: May 16, 2019
Focal, generalised epilepsy or both?
Aidan Neligan1,2, Umesh Vivekananda2, Josemir W Sander2,3
1Neurology, Homerton University Hospital NHS Foundation Trust, London, UK a.neligan@ucl.ac.uk.
None:
A 29-year-old woman presented with a witnessed convulsion, with semiology consistent with a focal-to-bilateral tonic-clonic seizure. Routine EEG supported a syndromic diagnosis of idiopathic generalised epilepsy with photosensitivity. We discuss the clinical utility of seizure semiology, highlighting the caveat that over-reliance or sole reliance on the ictal semiology may result in an erroneous diagnosis of focal epilepsy in someone with a generalised epilepsy.
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