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Updated: Jun 8, 2025

Isolation and Analysis of Brain-sequestered Leukocytes from Plasmodium berghei ANKA-infected Mice
Published on: January 2, 2013
A hypothesis to explain malaria-induced neurocognitive sequelae
Yuri Chaves Martins1, Cláudio Tadeu Daniel-Ribeiro2
1Department of Anesthesiology, Saint Louis University School of Medicine, Saint Louis, MO, USA.
Abstract:
The development of malaria-induced neurocognitive and behavioral sequelae is not entirely understood. We hypothesize that liver dysfunction caused by Plasmodium infection is responsible for malaria-induced neurocognitive and behavioral sequelae. Our metabolic hypothesis not only explains neurocognitive sequelae after cerebral malaria (CM) but also after other severe, non-severe, and asymptomatic malaria infections.
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