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Safety and efficacy of the Yamane technique for intraocular three-piece lens implantation in Egyptian patients diagnosed with Marfan syndrome: a retrospective study

  • 0Department of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Bmc Ophthalmology +

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November 5, 2024

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November 5, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

The Yamane technique (flanged intrascleral haptic fixation with double-needle technique) is safe and effective for Marfan syndrome patients with subluxated lenses, significantly improving visual acuity. Careful fundus examination is crucial to prevent complications like retinal detachment, especially in younger patients.

Area Of Science

  • Ophthalmology
  • Genetics
  • Surgical Techniques

Background

  • Marfan syndrome (MFS) frequently causes lens subluxation (ectopia lentis).
  • Intrascleral haptic fixation techniques are used for intraocular lens (IOL) implantation in such cases.

Purpose Of The Study

  • To evaluate the safety and efficacy of the Yamane technique (flanged intrascleral haptic fixation with double-needle technique) for IOL implantation.
  • To assess outcomes in Egyptian patients with Marfan syndrome and subluxated lenses.

Main Methods

  • Retrospective evaluation of 33 patients (40 eyes) with Marfan syndrome and subluxated lenses.
  • Lensectomy or phacoemulsification followed by IOL implantation using the Yamane technique.
  • Data collection included visual acuity, refraction, complications, and follow-up periods.

Main Results

  • Significant improvement in corrected distant visual acuity (CDVA) from 0.80 to 0.18 log MAR (P < 0.001).
  • Marked reduction in refractive errors: sphere from -9.1 D to -1.4 D, cylinder from -4.5 D to -1.4 D.
  • Low complication rate: IOL decentration (12.5%), vitreous hemorrhage (7.5%), IOL slippage/tilt (5%), and retinal detachment (5%).

Conclusions

  • The Yamane technique is a safe and effective option for treating subluxated lenses in Marfan syndrome patients.
  • Improved visual acuity was observed with manageable complications.
  • Pre- and post-operative fundus examinations are vital for early detection of retinal issues, particularly in younger patients prone to IOL tilting and slippage.

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