Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials01:16

Clinical Trials

6.6K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
6.6K
Exercise Stress Test01:26

Exercise Stress Test

176
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
176
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

740
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
740
Clinical Trials: Overview01:11

Clinical Trials: Overview

2.8K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
2.8K
Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

1.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.2K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sex-based differences in transition readiness and health-related quality of life during the healthcare transition of youth with special health care needs.

Clinics (Sao Paulo, Brazil)·2026
Same author

Food noise: Conceptual, methodological, and ethical considerations.

Appetite·2026
Same author

Exercise reprograms the gut microbiota to enhance metabolic outcomes after bariatric surgery: a translational, cross-species study.

International journal of obesity (2005)·2026
Same author

Effectiveness and feasibility of home-based physical exercise interventions for children and adolescents with chronic diseases: a systematic review and meta-analysis.

British journal of sports medicine·2026
Same author

International Manifesto for the Promotion of Physical Activity in the Post-COVID-19 Era: Overview, Challenges, and Perspectives.

Journal of physical activity & health·2026
Same author

Body Weight-Related Differences in Adipokines and Inflammatory Markers Among Women with Systemic Lupus Erythematosus.

Journal of inflammation research·2026

Related Experiment Video

Updated: Jun 8, 2025

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
00:07

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

9.6K

Exercise in Pediatric COVID-19: A Randomized Controlled Trial.

Camilla Astley, Jonathan A Drezner1, Sofia Mendes Sieczkowska

  • 1Department of Family Medicine, Center for Sports Cardiology, University of Washington, Seattle, WA.

Medicine and Science in Sports and Exercise
|November 6, 2024
PubMed
Summary

A 12-week home-based exercise training (HBET) program did not improve health-related quality of life (HRQOL) in pediatric COVID-19 survivors. However, HBET showed positive trends in improving cardiorespiratory fitness and heart rate recovery.

More Related Videos

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

1.0K
Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
07:40

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

7.2K

Related Experiment Videos

Last Updated: Jun 8, 2025

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
00:07

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

9.6K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

1.0K
Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
07:40

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

7.2K

Area of Science:

  • Pediatric medicine
  • Cardiovascular research
  • Exercise physiology

Background:

  • Pediatric COVID-19 can lead to prolonged symptoms affecting quality of life.
  • Home-based exercise training (HBET) is a potential intervention for post-COVID-19 recovery.
  • Assessing HBET's impact on pediatric COVID-19 patients' health is crucial.

Purpose of the Study:

  • To evaluate the effect of a 12-week HBET program on health-related quality of life (HRQOL) in pediatric COVID-19 patients.
  • To assess changes in cardiovascular and metabolic parameters following the HBET intervention.
  • To compare outcomes between HBET and standard care groups.

Main Methods:

  • A single-center, randomized controlled trial involving 32 pediatric COVID-19 patients post-discharge.
  • Participants were assigned to either HBET (supervised/unsupervised aerobic and bodyweight exercises) or standard care (CONTROL) in a 2:1 ratio.
  • Evaluations included HRQOL (Pediatric Quality of Life Inventory), cardiopulmonary exercise testing, endothelial function, and echocardiography.

Main Results:

  • No significant difference in HRQOL between the HBET and CONTROL groups.
  • A trend towards increased oxygen uptake (V̇O 2) at anaerobic threshold in the HBET group.
  • Significant improvements in peak heart rate, 1-min recovery, respiratory exchange ratio, and chronotropic response in the HBET group (sensitivity analysis).

Conclusions:

  • A 12-week HBET program did not significantly improve HRQOL in pediatric COVID-19 patients.
  • Exercise intervention demonstrated potential benefits for cardiorespiratory fitness parameters, including V̇O 2 at anaerobic threshold and heart rate recovery.
  • Further research is warranted to explore long-term effects of exercise on pediatric COVID-19 recovery, considering chronic conditions.