Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

6.3K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomarker-Driven Management of Nonmetastatic GEJ Adenocarcinoma.

Annals of surgical oncology·2026
Same author

UniST: A Unified Computational Framework for 3D Spatial Transcriptomics Reconstruction.

bioRxiv : the preprint server for biology·2026
Same author

Identifying Key Predictors of Metastatic Cutaneous Crohn's Disease: A Case-Control Study.

The American journal of gastroenterology·2026
Same author

Ethical considerations regarding environmental impact of generative artificial intelligence in dermatology.

Journal of the American Academy of Dermatology·2026
Same author

Horizon Scan of Emerging Issues at the Intersection of National Security, Artificial Intelligence, and Human Performance Enhancement.

Science and engineering ethics·2025
Same author

Psychosocial Impacts of Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer: A Narrative Review.

Psycho-oncology·2025

Related Experiment Video

Updated: Jun 8, 2025

A Training and Testing System for Performing Vascular Reconstruction In Vitro
09:52

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Published on: October 26, 2019

7.9K

A New Twist on the Surgeon's Knot: Quantifying Suture Security.

Omeed Modiri1, Joseph Ebriani1,2, Andrew Sauvageau1

  • 1Division of Dermatology, University of California, Los Angeles, Los Angeles, California.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|November 6, 2024
PubMed
Summary

Adding more twists to surgeon's knots improves suture security, with 3 to 5 twists offering the best balance for wound closure. Beyond five twists, the benefits for knot security diminish for certain suture sizes.

More Related Videos

Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair
09:00

Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair

Published on: November 12, 2021

2.0K
Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

5.6K

Related Experiment Videos

Last Updated: Jun 8, 2025

A Training and Testing System for Performing Vascular Reconstruction In Vitro
09:52

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Published on: October 26, 2019

7.9K
Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair
09:00

Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair

Published on: November 12, 2021

2.0K
Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

5.6K

Area of Science:

  • Surgical innovation
  • Biomedical engineering
  • Wound healing research

Background:

  • Surgical knot reliability is crucial for effective wound closure and healing.
  • The surgeon's knot, a modified square knot, uses extra twists to enhance friction and tissue stability.
  • Understanding knot security is essential for preventing complications.

Purpose of the Study:

  • To quantify the security of sutures based on the number of initial twists in a surgeon's knot.
  • To determine the optimal number of twists for maximal suture security.
  • To investigate the relationship between twist count and knot integrity.

Main Methods:

  • Utilized pig feet as a simulation model for surgical conditions.
  • Compared knot security using two suture types in three different sizes.
  • Evaluated the impact of one to six initial twists on knot security.
  • Employed univariable linear regression to analyze the association between twists and loosening force.

Main Results:

  • Suture security generally increased with a higher number of initial twists.
  • Optimal knot security was observed with up to five twists.
  • Diminishing returns in security benefits were noted beyond five twists for specific suture sizes.

Conclusions:

  • Increasing twists in surgeon's knots significantly enhances suture integrity.
  • The optimal range for surgeon's knot security is between 3 to 5 twists.
  • A balance between knot security and ease of application is necessary for surgical practice.