Related Experiment Video
Updated: Jun 8, 2025
Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
[Severe coronavirus-2 infection background for cardiovascular complications]
Juan Angel Cibrian-Delgado1, Maraí Xóchitl Gutiérrez-Galván1, Agustin Ramiro Urzua-Gonzalez1
1Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Departamento de Cardiología. León, Guanajuato, México.
Insights
Severe COVID-19 (coronavirus disease 2019) increases the risk of long-term cardiovascular complications and rehospitalization. Patients experienced higher rates of endocarditis, arrhythmias, and thrombotic events following severe infection.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) can cause long-term cardiovascular issues due to inflammation and endothelial damage.
- The long-term cardiovascular risk for patients with severe COVID-19 compared to those without is not well-established.
Purpose of the Study:
- To compare the incidence of cardiovascular complications in patients with a history of severe SARS-CoV-2 infection against a control population.
- To identify specific cardiovascular sequelae associated with severe COVID-19.
Main Methods:
- An observational analytical cohort study included 988 patients.
- Electronic medical records were used to measure outcomes and compare variables.
- Descriptive statistical analyses were performed.
Main Results:
- Severe COVID-19 history correlated with increased cardiovascular rehospitalization risk.
- Higher frequencies of endocarditis, arrhythmias, and thrombotic events were observed.
- Type 4a myocardial infarcts and right atrial thrombi were more prevalent in severe COVID-19 patients.
Conclusions:
- COVID-19 is linked to elevated hospital readmissions for cardiac conditions like endocarditis and arrhythmias.
- A sustained negative impact on long-term cardiovascular health is evident in patients with severe COVID-19.
Background:
Covid-19 infection can affect the cardiovascular system in the long term, due to the inflammation and endothelial damage caused by SARS-CoV-2. It is unknown whether patients who have had severe covid-19 have a higher risk of cardiovascular complications than those who have not.
Objective:
To compare the presentation of cardiovascular complications in patients with a history of severe SARS-CoV-2 infection and population without this history.
Material And Methods:
An observational analytical cohort study was conducted that included 988 patients, with a calculation for the sample size to detect a minimum RR of 1.5 with a statistical power of 80%. The outcome was measured through electronic medical records and variables were compared. A descriptive analysis was performed using measures of central tendency and dispersion for quantitative variables and absolute and relative frequencies for qualitative variables.
Results:
The history of severe covid-19 infection is related to a higher risk of rehospitalization for cardiovascular causes. There was an increase in the frequency of endocarditis, arrhythmias and thrombotic events. Type 4a infarcts and thrombi in the right atrium were more common in patients with covid-19.
Conclusions:
Covid-19 was associated with a higher hospital readmission for cardiac problems, such as endocarditis and arrhythmias. A persistent negative impact on long-term cardiovascular health was identified in these patients.
More Related Videos
08:41Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
07:56Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
Published on: May 5, 2023
Related Concept Videos
01:21Myocarditis I: Introduction
01:27Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
01:25Endocarditis II: Clinical features and Diagnostic Tests
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
01:23Rheumatic Heart Disease I: Introduction
01:20COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...