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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
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Prostate cancer theragnostics biomarkers: An update
Sathish Kumar Am1, Prabhakar Rajan2, Mohammad Alkhamees3
1Prostate Cancer Biomarker Laboratory, Faculty of Clinical Research, Sri Ramachandra Institute of Higher Education & Research, Chennai, India.
Investigative and Clinical Urology
|November 6, 2024
Summary
Prostate cancer biomarkers are crucial for early detection and treatment decisions. Combining immunotherapy with effective biomarkers improves patient outcomes, aiding in diagnosis and therapy selection.
Area of Science:
- Oncology
- Biochemistry
Background:
- Biomarkers, including proteins and genes, are essential for determining tumor stage.
- Prostate cancer biomarkers are pivotal for treatment strategies, especially when combined with immunotherapy.
Purpose of the Study:
- To review the progress in identifying prostate cancer biomarkers.
- To highlight biomarkers for classification, prediction, and prognostication.
- To discuss biomarkers as targets for clinical intervention.
Main Methods:
- Literature review of current research on prostate cancer biomarkers.
- Analysis of biomarker applications in early detection programs.
- Summary of biomarker roles in treatment selection.
Main Results:
- Biomarkers aid in identifying asymptomatic individuals needing biopsy.
- Biomarkers help select patients who benefit from definitive medical treatment.
- Significant progress has been made in identifying diverse prostate cancer biomarkers.
Conclusions:
- Prostate cancer biomarkers are vital for early detection and personalized treatment.
- The combination of immunotherapy and biomarkers offers a beneficial therapeutic strategy.
- Continued research into biomarkers will enhance prostate cancer management and clinical intervention.
