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Updated: Jul 18, 2026

In Vitro Growth of Mouse Preantral Follicles Under Simulated Microgravity
Published on: December 17, 2017
Cellular response in three-dimensional spheroids and tissues exposed to real and simulated microgravity: a narrative
Daan W A van den Nieuwenhof1, Lorenzo Moroni2, Joshua Chou3
1Department of Otorhinolaryngology, Radboud University Medical Center, Nijmegen, The Netherlands. daan.vandennieuwenhof@radboudumc.nl.
Abstract:
The rising aging population underscores the need for advances in tissue engineering and regenerative medicine. Alterations in cellular response in microgravity might be pivotal in unraveling the intricate cellular mechanisms governing tissue and organ regeneration. Microgravity could improve multicellular spheroid, tissue, and organ formation. This review summarizes microgravity-induced cellular alterations and highlights the potential of tissue engineering in microgravity for future breakthroughs in space travel, transplantation, drug testing, and personalized medicine.
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