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Simultaneous multi-slice cardiac real-time MRI at 0.55T.

Ecrin Yagiz1, Parveen Garg2, Steven Y Cen3,4

  • 1Ming Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.

Magnetic Resonance in Medicine
|November 7, 2024
PubMed
Summary

Simultaneous multi-slice (SMS) real-time MRI at 0.55T is feasible for cardiac function evaluation. This method provides adequate contrast for assessing left-ventricular function across three slices without gating.

Keywords:
0.55 tesla MRIcardiac functionreal‐time MRIsimultaneous multi‐slice

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Area of Science:

  • Cardiovascular Imaging
  • Magnetic Resonance Imaging
  • Medical Physics

Background:

  • Cardiac CINE MRI is standard for left-ventricular (LV) function assessment.
  • Sequential multi-slice balanced SSFP (bSSFP) requires ECG gating and breath-holds.
  • Simultaneous multi-slice (SMS) imaging reduces breath-holds in CINE MRI at higher field strengths.

Purpose of the Study:

  • To assess the feasibility of SMS real-time MRI (RT-MRI) at 0.55T for cardiac function.
  • To determine if SMS is effective for RT-MRI evaluation of cardiac function.
  • To compare SMS with single-band (SB) imaging at 0.55T.

Main Methods:

  • Implemented an SMS bSSFP pulse sequence with golden-angle spirals at 0.55T (SMS factor of three).
  • Acquired data covering the LV with three SMS acquisitions and nine SB acquisitions.
  • Utilized spatio-temporal constrained reconstruction and analyzed images for contrast and Edge Sharpness (ES).

Main Results:

  • A statistically significant 2-fold difference in blood-myocardium contrast was observed between SMS and SB.
  • Contrast values at mid-diastole/end-systole: SMS 13.38/10.79, SB 29.05/22.26.
  • No significant difference in Edge Sharpness (ES) scores between SMS and SB.

Conclusions:

  • SMS cardiac RT-MRI at 0.55T is feasible.
  • The technique provides sufficient contrast for LV function evaluation.
  • Simultaneous assessment of three slices is possible without gating or motion assumptions.