Doxycycline Trap: A Case Report on the Unexpected Development of an Oesophageal Ulcer

The phenomenon of drug-induced mucosal damage has not been reported much in the literature, although over 100 drugs are known to cause this condition. Tetracyclines contribute the most to mucosal damage. The common symptoms are difficulty swallowing, pain while swallowing, and possibly retrosternal pain. The diagnosis is based on upper endoscopy. The therapeutic approach involves discontinuing the causative drug, switching to parenteral fluid intake, and administering proton pump inhibitors and antacids. Proper drug intake in an upright position with plenty of fluids is key to preventing mucosal damage.