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Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
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Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) in a 32-Year-Old

Rabail Karim1, Munzir Malik2, Hamza Cheema2

  • 1Neurology, The Walton Centre, Liverpool, GBR.

Cureus
|November 7, 2024
PubMed

This case report describes a 32-year-old male with a familial history of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), presenting with right-sided weakness and visual disturbances. The symptoms, consistent with a transient ischemic attack (TIA), resolved spontaneously. Subsequent evaluation, including MRI brain imaging, revealed a high T2 signal in subcortical white matter in the frontal and parietal lobes, consistent with CADASIL. Positive NOTCH3 testing confirmed the diagnosis, leading to the initiation of antiplatelet and statin therapy under the care of both stroke and neurology teams.

Keywords:
and transient ischemic attack (tia)cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil)cerebro-vascular accident (stroke)migraine disordervascular spasm

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