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Chronic Obstructive Pulmonary Disease-Associated Mortality - China, 2014-2021
Zifang Zhou1, Lijun Wang1, Maigeng Zhou1
1National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Chronic obstructive pulmonary disease (COPD) mortality in China significantly decreased from 2014 to 2021. However, the burden of COPD remains high in underdeveloped regions, highlighting disparities in healthcare access and outcomes.
Area of Science:
- Public Health
- Epidemiology
- Respiratory Medicine
Background:
- China faces a substantial and increasing burden of chronic obstructive pulmonary disease (COPD).
- Traditional mortality estimations often overlooked COPD's role as a comorbidity.
- This study provides a comprehensive analysis of COPD-associated mortality using detailed death certificate information.
Purpose of the Study:
- To estimate COPD-associated mortality in China from 2014 to 2021.
- To analyze trends in COPD mortality stratified by demographic and geographic factors.
- To identify major comorbidities contributing to COPD-related deaths.
Main Methods:
- Retrospective analysis of the National Mortality Surveillance System (NMSS) data from 2014-2021.
- Calculation of age-standardized mortality rates (ASMRs) by sex, region, and residence.
- Application of Joinpoint regression to determine average annual percentage change (AAPC) in mortality rates.
Main Results:
- COPD-associated ASMR in China decreased significantly from 91.85 to 45.90 per 100,000 population between 2014 and 2021.
- Mortality rates declined unevenly across genders, regions (eastern, central, western), and residential areas (urban, rural).
- Cardiovascular diseases and other respiratory conditions were identified as major comorbidities in COPD-associated deaths.
Conclusions:
- COPD is a critical comorbidity contributing significantly to mortality in China.
- Despite an overall substantial decrease in COPD-associated mortality, the disease burden persists, particularly in less developed regions.
- Addressing regional disparities is crucial for mitigating the impact of COPD in China.
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