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A portable, pre-programmable insulin infusion system in diabetes mellitus
Hormone and Metabolic Research. Supplement Series
|January 1, 1979
Summary
A new portable insulin pump helps manage blood glucose in children with diabetes. Achieving normal blood sugar levels requires precise insulin dosing with programmed infusion patterns.
Area of Science:
- Biomedical Engineering
- Endocrinology
- Diabetes Management
Background:
- Juvenile-onset diabetes requires continuous insulin management.
- Pre-programmed insulin infusion offers a potential method for improved glycemic control.
Purpose of the Study:
- To evaluate the efficacy of a miniaturized portable pump for delivering pre-programmed insulin infusion patterns.
- To assess the impact of these patterns on blood glucose levels in juvenile-onset diabetics.
Main Methods:
- Development of a miniaturized portable insulin pump.
- Study involving six juvenile-onset, insulin-requiring diabetic patients.
- Seven insulin infusion periods, each lasting up to four days.
Main Results:
- The mean blood glucose level observed was 7.0 +/- 2.3 mmol/l.
- The mean amplitude of glycemic excursions was 5.0 +/- 1.4 mmol/l.
- Variability in blood glucose levels was noted despite programmed infusion.
Conclusions:
- The miniaturized portable pump is a viable tool for studying insulin infusion patterns.
- Achieving normoglycemia (normal blood glucose) is contingent upon accurate insulin dose selection.
- Further research is needed to optimize insulin dosing algorithms for improved glycemic control.