Effects of Message Framing on Human Papillomavirus Vaccination: Systematic Review

Area of Science:

• Public Health
• Health Communication
• Vaccinology

Background:

• Promoting human papillomavirus (HPV) vaccination is crucial for cervical cancer elimination.
• The optimal message framing for HPV vaccination promotion remains debated.
• This study investigates the impact of gain-loss message framing on HPV vaccination.

Approach:

• A systematic review following PRISMA guidelines was conducted.
• Searched major databases (PubMed, Embase, Scopus, Web of Science) up to August 2023.
• Included 19 intervention studies on message framing for HPV vaccination eligibility.

Key Points:

• Gain-loss framing did not significantly impact vaccination attitudes or intentions.
• Loss framing showed a slight, inconclusive advantage for attitudes and intentions.
• The effect of gain-loss framing on HPV vaccination behaviors could not be determined due to limited data.

Conclusions:

• Combining gain-loss framing with other strategies may improve message effectiveness.
• Further high-quality research on message framing and mediators/moderators is necessary.
• Enhanced message framing strategies are needed to boost HPV vaccination rates.