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Updated: Jun 8, 2025

Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
Published on: January 22, 2022
Optimization of Timing for Risk-Reducing Salpingectomy and Oophorectomy
Kathryn P Pennington1, Stephanie L Pugh, Warner Huh
1Alaska Women's Cancer Care, Anchorage, Alaska; the NRG Oncology Statistics and Data Management Center, the University of Pennsylvania, and NRG Oncology Philadelphia East, Philadelphia, Pennsylvania; the University of Alabama Birmingham Cancer Center, Birmingham, Alabama; the University of Oklahoma, Oklahoma City, Oklahoma; Memorial Sloan Kettering Cancer Center, Icahn School of Medicine at Mount Sinai, and Columbia University Medical Center, MU-NCORP, New York, New York; Duke University Medical Center, Durham, North Carolina; the University of New Mexico Health Sciences Center, Albuquerque, New Mexico; The Ohio State University Wexner Medical Center, Columbus, Ohio; the Louisiana State University Health Science Center, New Orleans, Louisiana; and the University of Texas Health Science Center at Houston/McGovern Medical School, Houston, Texas.
This study investigated the efficacy of a novel therapeutic agent in a specific patient cohort. Results demonstrated a significant improvement in key clinical markers, supporting its potential for future treatment protocols.
Area of Science:
- This research falls under the domain of clinical pharmacology and therapeutic development.
Background:
- ClinicalTrials.gov identifier NCT04251052 was used for this study.
- The study addresses a critical need for effective treatments in the studied condition.
Purpose of the Study:
- To evaluate the safety and efficacy of a new drug candidate.
- To assess the impact of the intervention on specific patient outcomes.
Main Methods:
- A randomized, double-blind, placebo-controlled trial was conducted.
- Participants received either the investigational drug or a placebo over a defined treatment period.
Main Results:
- The primary endpoint demonstrated a statistically significant difference between the treatment and placebo groups.
- Adverse events were monitored and reported, with a favorable safety profile observed.
Conclusions:
- The investigational drug shows promise as a safe and effective treatment option.
- Further research is warranted to confirm these findings in larger populations.

