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Updated: Jun 8, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Dirhodium-Catalyzed [2 + 2 + 2] Cycloaddition of 1,6-Diynes and Alkynes
Xiang Gao1, Wendeng Li1, Yang Chen1
1Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China.
Abstract:
A facile method for the construction of fused arenes has been developed through dirhodium-catalyzed [2 + 2 + 2] cycloaddition, which represents a new application of dirhodium complexes. This protocol is convenient to handle without the addition of extra ligands and reductants and tolerates a broad range of functional groups. Mechanistic studies revealed that the two-electron oxidation process, carboxylate ligand departure, and heteroatom coordination-promoted [2 + 2 + 2] cycloaddition were possibly involved.
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