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Updated: Jun 8, 2025

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
Published on: February 10, 2015
Delayed onset autoimmune cholangitis in a patient treated with pembrolizumab
Joshua Newington1, Daniel Patterson2, Pilar Sanchez3
1Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0SP, United Kingdom.
Abstract:
This case study describes a female patient in her late 70s who developed autoimmune cholangitis a year after finishing 35 cycles of pembrolizumab for the treatment of her non-small cell lung cancer. The diagnosis was initially missed and delayed; the patient's agoraphobia and the COVID-19 pandemic were noted as contributing factors.
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